Boc-Leu-Gly-Arg-AMC
规格
Cas Number | 65147-09-3(DMSO) |
规格或纯度 | 10mM in DMSO |
包装 | 1ml |
产品信息
品牌 | 阿拉丁 |
浓度 | 10mM in DMSO |
过滤标签 | Amino Acid Derivatives,Compound libraries |
储存温度 | 避光,干燥,-80℃储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | Boc-Leu-Gly-Arg-AMC 是转化酶的含氟 AMC 底物。Boc-Leu-Gly-Arg-AMC 可用于酶测定。 |
英文描述 |
Boc-Leu-Gly-Arg-AMC is a fluorogenic AMC substrate for the convertases. Boc-Leu-Gly-Arg-AMC can be used in enzymatic assays. In Vitro To demonstrate the presence in the abdominal gland of proteolytic enzymes capable of generating Sodefrin, an enzymatic assay was developed using Boc-Leu-Gly-Arg-AMC as synthetic substrate. A crude extract of the abdominal gland hydrolyzed Boc-Leu-Gly-Arg-AMC to liberate 7-amino-4- methylcoumarin, suggesting that enzymes that generate sodefrin from its precursor molecule are present in the gland. The activity in the extract for cleaving Boc-Leu-Gly-Arg-AMC is optimal at pH 9.0 and 45 ℃. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |