Casein Kinase II Inhibitor IV
规格
| Cas Number | 863598-09-8 |
| 规格或纯度 | Moligand™, ≥95% |
| 级别 | Moligand™ |
| 纯度 | ≥95% |
| 包装 | 100mg 或 50mg 或 10mg 或 1mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | Soluble in ethanol, and DMSO. |
| 简短描述 | 酪蛋白激酶II的细胞渗透性ATP竞争性抑制剂 |
| 英文简短描述 | a cell-permeable ATP-competitive inhibitor of caseing kinase II |
| 过滤标签 | Casein Kinase,Cell Cycle/DNA Damage,Stem Cell/Wnt,Casein kinase II 抑制剂 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 物理形态 | 固体 |
| 描述 |
角质形成细胞分化诱导剂，可渗透细胞的吡咯并嘧啶酮化合物，作为酪蛋白激酶II（IC | 50 | = 9 nM）的有效，ATP竞争性抑制剂，是正常人角质形成细胞（NHEK）分化的有效诱导剂（EC | 50 | = 100 nM）。也有报道直接或间接与细胞TANK结合激酶1（TBK1）和NIMA相关激酶9（NEK9）相互作用。 |
| 英文描述 |
Keratinocyte Differentiation Inducer cell-permeable pyrrolo-pyrimidone compound that acts as a potent, ATP-competitive inhibitor of casein kinase II (IC|50|= 9 nM) and an effective inducer of normal human keratinocytes (NHEK) differentiation (EC|50|= 100 nM). Also reported to interact, direcly or indirectly, with cellular TANK-binding Kinase 1 (TBK1) and NIMA-related kinase 9 (NEK9). |