Certepetide
规格
| Cas Number | 2580154-02-3 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 过滤标签 | Integrin,Complement System,Immunology/Inflammation,Cytoskeleton |
| 储存温度 | 避光,充氩,干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | Certepetide (CEND-1) 是一种双功能环肽（又称 iRGD）。Certepetide 是一种肿瘤穿透增强剂，通过 RGD 基序与α-av-整合素相互作用，并通过激活 NRP-1 ，将实体瘤微环境转化为一个临时的拮抗剂。 |
| 英文描述 |
Certepetide (CEND-1) is a bifunctional cyclic peptide (a.k.a. iRGD). Certepetide is a tumor-penetrating enhancer via RGD motif interaction with alphav-integrins and via activating NRP-1 , and transforms the solid tumor microenvironment into a temporary agent conduit. Certepetide accumulates in tumors, and is used in the research of pancreatic cancer and other solid tumors Form:Solid IC50& Target:Alphav-integrins, NRP-1 |