FLT3-IN-4
规格
Cas Number | 2304799-09-3(DMSO) |
规格或纯度 | 10mM in DMSO |
包装 | 1ml |
产品信息
品牌 | 阿拉丁 |
浓度 | 10mM in DMSO |
过滤标签 | FLT3,Protein Tyrosine Kinase/RTK,Compound libraries |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | FLT3-IN-4 是一种口服有效的 Fms 样酪氨酸受体激酶 3(FLT3;IC 50 =7 nM)抑制剂,可用于治疗急性髓性白血病。 |
英文描述 |
FLT3-IN-4 is a potent and orally effective Fms-like tyrosine receptor kinase 3 ( FLT3 ; IC 50 =7 nM) inhibitor for treating acute myelogenous leukemia. In Vitro FLT3-IN-4 (Compound 9u) shows potent inhibitory activities against MV4-11 and Molm-13 cells with IC 50 values are 0.089±0.001 nM and 0.022±0.003 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |