I-BET762 carboxylic acid
规格
| Cas Number | 1300019-38-8 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 50mg 或 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 7.14 mg/mL (17.99 mM; Need ultrasonic) |
| 过滤标签 | 表观遗传学,Epigenetic Reader Domain,Ligands for Target Protein for PROTAC,PROTAC |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | I-BET762 羧酸（Molibresib carboxylic acid）是一种基于 I-BET762 的弹头配体，用于 PROTAC 靶向 BET 的共轭反应。I-BET762 羧酸（Molibresib 羧酸）是一种 BRD4 抑制剂，pIC 50 为 5.1。 |
| 英文描述 |
I-BET762 carboxylic acid (Molibresib carboxylic acid) is an I-BET762-based warhead ligand for conjugation reactions of PROTAC targeting on BET. I-BET762 carboxylic acid (Molibresib carboxylic acid) is a BRD4 inhibitor with a pIC 50 of 5.1 In Vitro I-BET762 carboxylic acid (Molibresib carboxylic acid) (Compound 27) inhibits peripheral blood mononuclear cells (PBMC) with a pIC 50 of <4. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:BRD4 5.1 (pIC 50 ) |