JWG-071
规格
| Cas Number | 2250323-50-1(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | ERK,Stem Cell/Wnt,MAPK/ERK Pathway,Compound libraries |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | JWG-071 是首个报道的 ERK5 激酶选择性化学探针。JWG-071 提高了 ERK5 的活性和 BRD4 的选择性。JWG-071 将成为解构 ERK5 和 BRD4 药理学所急需的化学探针。 |
| 英文描述 |
JWG-071 is the first reported kinase-selective chemical probe for ERK5 . JWG-071 improves ERK5 activity and BRD4 selectivity. JWG-071 will be a much-needed chemical probe for deconvoluting ERK5 and BRD4 pharmacology In Vitro JWG-071 inhibits ERK5 and LRRK2 with IC 50 of 88 and 109 nM, respectively. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:ERK5 88 nM (IC 50 ) |