Litronesib
规格
Cas Number | 910634-41-2 |
规格或纯度 | ≥97% |
纯度 | ≥97% |
包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg 或 2mg |
产品信息
品牌 | 阿拉丁 |
Action Type | 抑制剂 |
Mechanism Of Action | 驱动蛋白样蛋白 1 抑制剂 |
溶解性 | DMSO : ≥ 50 mg/mL (97.71 mM) |
过滤标签 | Kinesin,Cell Cycle/DNA Damage,Cytoskeleton |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | Litronesib(LY2523355)是一种选择性有丝分裂特异性驱动蛋白 Eg5 抑制剂,具有抗肿瘤活性。 |
英文描述 |
Litronesib (LY2523355) is a selective Eg5 inhibitor. Litronesib (25 nM) induces cancer cells to death during mitotic arrest, and this needs sustained activation of spindle-assembly checkpoint (SAC). MCE has not independently confirmed the accuracy of these methods. |