Litronesib

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¥ 17,499.90 17499.9 CNY ¥ 17,499.90

¥ 1,800.90

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规格或纯度 ≥97%
货号(SKU) L650229
品牌 阿拉丁
  • 包装

此组合不存在。

条款和条件
30天退款保证
运输:2-3 个工作日

规格


Cas Number 910634-41-2
规格或纯度 ≥97%
纯度 ≥97%
包装 100mg50mg10mg5mg25mg2mg

产品信息


品牌 阿拉丁
Action Type 抑制剂
Mechanism Of Action 驱动蛋白样蛋白 1 抑制剂
溶解性 DMSO : ≥ 50 mg/mL (97.71 mM)
过滤标签 Kinesin,Cell Cycle/DNA Damage,Cytoskeleton
储存温度 -20°C储存
运输条件 超低温冰袋运输
生化和生理学机理 Litronesib(LY2523355)是一种选择性有丝分裂特异性驱动蛋白 Eg5 抑制剂,具有抗肿瘤活性。
英文描述

Litronesib (LY2523355) is a selective Eg5 inhibitor. Litronesib (25 nM) induces cancer cells to death during mitotic arrest, and this needs sustained activation of spindle-assembly checkpoint (SAC). MCE has not independently confirmed the accuracy of these methods.

Litronesib (LY2523355; 1.1, 3.3, 10, and 30 mg/kg, i.v.) shows antitumor activity in a dose-dependently, and causes a dramatic increase in cancer cells immuno-positive for histone H3 phosphorylation in Colo205 xenograft tumors .

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