卡铂

Product Description
Carboplatin is believed to form inter- and intrastrand DNA adducts which activate signaling pathways culminating in apoptosis. The development of carboplatin was inspired from the efficacy of its progenitor, Cisplatin (sc-200896), the first of this class of antineoplastic agents. The action of this group of platinum-based compounds is primarily attributed to DNA adduct formation, however, these molecules also bind other biological molecules, including enzymes, which might play a role in their mechanism of action.
An antitumor agent that binds to DNA leading to apoptosis

Product Application
Carboplatin has been used: in chemotherapy-induced thrombocytopenia mouse model and treatment to induce cell death in a large subset of colorectal cancer cells in the evaluation of cell proliferation and chemosensitivity 

as a positive control for suppressed cell growth

Product class
hAPIs, Metal based hAPIs

Chemical properties