甲磺酸盐西地那非
规格
| Cas Number | 1308285-21-3 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 5g 或 100mg 或 250mg 或 1g 或 500mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | Solubility (25°C) In vitro DMSO: 100 mg/mL Water: 100 mg/mL Ethanol: 4 mg/mL |
| 简短描述 | PDE5 选择性抑制剂 |
| 英文简短描述 | PDE5 Selective Inhibitors |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 甲磺酸西地那非是西地那非的甲磺酸盐，是磷酸二酯酶 5 的抑制剂。 |
| 英文描述 |
Information Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor ofPhosphodiesterase 5. Targets PDE5 In vivo Chronic sildenafil treatment increases the detumescence phase in young and aged rats (p<0.05), although aged rats show a greater increase than young rats. Baseline cavernous PDE5 expression and activity are greater in aged vs young rats (p<0.05). After chronic sildenafil treatment cavernous PDE5 expression is increased in young (p<0.05) but not in aged rats. Chronic and acute sildenafil treatment similarly inhibits PDE5 activity in the penis of young and aged rats (p<0.05), coincident with its free plasma concentrations equivalent to clinically therapeutic ranges. |