(2R)-Octyl-α-hydroxyglutarate
规格
Cas Number | 1391194-67-4 |
规格或纯度 | ≥98% |
纯度 | ≥98% |
包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg |
产品信息
品牌 | 阿拉丁 |
溶解性 | DMSO : 100 mg/mL (384.13 mM; Need ultrasonic) |
储存温度 | 2-8°C储存,干燥 |
运输条件 | 冰袋运输 |
生化和生理学机理 | (2R)-辛基-α-羟基戊二酸酯((2R)-辛基-2-HG)是 D-异构体 2-羟基戊二酸酯的一种改良形式。 |
英文描述 |
(2R)-Octyl-α-hydroxyglutarate ((2R)-Octyl-2-HG) is a modified form of D-isomer 2-Hydroxyglutarate. In Vitro Treatment of IDH1-WT HeLa cells with (2R)-Octyl-α-hydroxyglutarate, a modified form of 2-Hydroxyglutarate with high cellular uptake, results in a dose-dependent increase in DSBs in log-phase cells. It has been used to examine the contribution of D-2-Hydroxyglutarate to the oxidative mitochondrial processes of IDH1-mutated cancer cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |