ALW-II-49-7
规格
| Cas Number | 1135219-23-6(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | Ephrin Receptor,Protein Tyrosine Kinase/RTK,Compound libraries |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | ALW-II-49-7 是一种选择性 EphB2 激酶抑制剂，在细胞中的 EC 50 值为 40 nM。 |
| 英文描述 |
ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC 50 value of 40 nM in cell In Vitro ALW-II-49-7 (compound 9) exhibits selectivity profile of binding to a set of kinases including b-raf, CSF1R, DDR1, DDR2, EphA2, EphA5, EphA8, EphB1, EphB2, EphB3, Frk, Kit, Lck, p38a, p38b, PDGFRa, PDGFRb, and Raf1. ALW-II-49-7 (0.01-10 μM; 1 h) inhibits EphB2 tyrosine kinase activity in U87 glioblastoma cells. EphB2 is added in media at 2 μg/mL. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:EphB2 |