AN-9
规格
Cas Number | 122110-53-6 |
规格或纯度 | ≥95% |
纯度 | ≥95% |
包装 | 250mg 或 1g 或 50mg 或 5mg 或 25mg |
产品信息
品牌 | 阿拉丁 |
溶解性 | Soluble in DMSO (≥10 mg/ml). |
简短描述 | 具有抗转移和抗血管生成特性的HDAC抑制剂 |
英文简短描述 | an HDAC inhibitor with antimetastic and antiangiogenic properties |
过滤标签 | 表观遗传学,HDAC,Bcr-Abl,Cell Cycle/DNA Damage,Protein Tyrosine Kinase/RTK |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | Pivanex (AN-9), a derivative of Butyric acid, is an orally active HDAC inhibitor. Pivanex down-regulates bcr-abl protein and enhances apoptosis. Pivanex has antimetastic and antiangiogenic properties. |
描述 |
AN-9是具有抗转移和抗血管生成特性的HDAC抑制剂。从理论上讲,AN-9可减少血管形成以及bFGF和HIF-1的表达 |
英文描述 |
AN-9 is an HDAC inhibitor with antimetastic and antiangiogenic properties. AN-9 is theorized to reduce vascularization and the expression of bFGF and HIF-1 |