ANO1-IN-1
规格
| Cas Number | 407587-01-3 |
| 规格或纯度 |
| 包装 | 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 过滤标签 | Chloride Channel,膜转运器/离子通道 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | ANO1-IN-1 （化合物 9c）是一种选择性 ANO1 通道阻断剂，对 ANO1 和 ANO2 的 IC 50 分别为 2.56 μM 和 15.43 μM。ANO1-IN-1 能强烈抑制胶质母细胞瘤细胞的增殖。 |
| 英文描述 |
ANO1-IN-1 (Compound 9c) is a selective ANO1 channel blocker with an IC 50 of 2.56 μM and 15.43 μM against ANO1 and ANO2 , respectively. ANO1-IN-1 suppresses strongly proliferation of glioblastoma cells In Vitro ANO1-IN-1 (Compound 9c) (10 μM) significantly suppresses migration and invasion of U251 cells. ANO1-IN-1 and TMZ combination brings about remarkable synergistic effects in suppressing proliferation of GBM cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC 50 : 2.56 μM (ANO1), 15.43 μM (ANO2) |