Apelin-12
规格
| Cas Number | 229961-08-4 |
| 规格或纯度 |
| 包装 | 10mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : ≥ 100 mg/mL (70.29 mM) |
| 过滤标签 | HIV,Anti-infection |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | Apelin-12是多肽最有效的C端片段之一，与孤儿受体APJ受体具有很高的亲和力。Apelin-12 参与体液平衡的调节和进食的中枢控制。Apelin-12 |
| 英文描述 |
Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect In Vitro Apelin-12 (A12) exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and p38 MAPK signaling pathway in mouse. Administration of exogenous A12 reduces arterial blood pressure in anesthetized rats due to activation of endothelial nitric oxide synthase and exerts a positive inotropic action in failing myocardium of rodents. Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:HIV-1 |