Carcinoembryonic Antigen (CEA)

癌胚抗原（CEA）是一种存在于发育中婴儿（胎儿）某些组织中的蛋白质。
体外活性：Carcinoembryonic Antigen（CEA）用作肺癌的肿瘤标志物。CEA还用作预后和预测性标志物。CEA是一种参与细胞粘附的糖蛋白，通常在胎儿发育期间产生，但在出生前停止产生。CEA是一种糖基磷脂酰肌醇（GPI）-细胞表面锚定糖蛋白，其特化的硫酸乙酰富科索糖型糖型作为结肠癌L-选择素和E-选择素配体发挥作用，这对结肠癌细胞的转移性传播可能至关重要。

Carcinoembryonic antigen (CEA) is a protein that is present in certain tissues of a developing baby (fetus).
Carcinoembryonic Antigen (CEA) serves as a tumor marker for lung cancer and is utilized for both prognostic and predictive purposes. As a glycoprotein that plays a role in cell adhesion, CEA is typically produced during fetal development, with its production ceasing before birth. It is a glycosyl phosphatidyl inositol (GPI)-anchored cell surface glycoprotein, with its sialofucosylated glycoforms functioning as colon carcinoma L-selectin and E-selectin ligands. This characteristic is crucial for the potential metastatic spread of colon carcinoma cells.