CB2R/FAAH modulator-2
规格
| Cas Number | 2876918-68-0 |
| 规格或纯度 |
| 包装 | 10mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 过滤标签 | Cannabinoid Receptor,FAAH,GPCR/G Protein,神经元信号传导,Metabolic Enzyme/Protease |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | CB2R/FAAH 调节剂-2（化合物 26）是一种双靶向调节剂，既是 CB2R 激动剂，又是 FAAH 抑制剂。CB2R/FAAH 调节剂-2 对 CB2R 和 CB1R 的 K i 值分别为 10.8 和 152.9 nM，对 FAAH 的 IC 50 值为 6.2 μM。CB2R/ |
| 英文描述 |
CB2R/FAAH modulator-2 (compound 26) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The K i values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC 50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer , deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection In Vitro CB2R/FAAH modulator-2 (compound 26)(10 μM) reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β and IL6 in unstimulated monocytes and macrophages. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:CB1 152.9 nM (Ki) CB2 10.8 nM (Ki) |