DHODH-IN-16
规格
Cas Number | 2511248-11-4(DMSO) |
规格或纯度 | 10mM in DMSO |
包装 | 1ml |
产品信息
品牌 | 阿拉丁 |
浓度 | 10mM in DMSO |
过滤标签 | DNA/RNA Synthesis,Dihydroorotate Dehydrogenase,Cell Cycle/DNA Damage,Metabolic Enzyme/Protease,Compound libraries |
储存温度 | -80℃储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | DHODH-IN-16 是一种强效的二氢烟酸脱氢酶(DHODH)抑制剂,对人类 DHODH 的 IC 50 为 0.396 nM。 |
英文描述 |
DHODH-IN-16 is a potent dihydroorotate dehydrogenase (DHODH) inhibitor with an IC 50 of 0.396 nM for human DHODH In Vitro DHODH-IN-16 (Example 22) potently inhibits the growth of MOLM-13 cells with an IC 50 of 0.2 nM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.396 nM (human DHODH) |