DUB-IN-2
规格
| Cas Number | 924296-19-5(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | Deubiquitinase,Cell Cycle/DNA Damage,Compound libraries |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | DUB-IN-2 是一种强效去泛素化酶抑制剂，对 USP8 的 IC 50 为 0.28 μM。 |
| 英文描述 |
DUB-IN-2 is a potent deubiquitinase inhibitor with an IC 50 of 0.28 μM for USP8 In Vitro DUBs-IN-2 (compound 22 e) is a potent USP8 inhibitor with an IC 50 of 0.28 μM, and has no effect on USP7, with an IC 50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC 50 values of 0.5-1.5 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. IC50& Target:IC50: 0.28 μM (USP8) |