ex229(化合物991)
规格
| Cas Number | 1219739-36-2 |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 简短描述 | AMPK 活化剂 |
| 英文简短描述 | AMPK Activators |
| 过滤标签 | Compound libraries |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | EX229（化合物 991）是一种强效的 AMPK 激活剂，其激活 AMPK 的效力是 A769662 的 5-10 倍。 |
| 描述 |
EX229 (compound 991)是一种有效的AMPK激活剂，其效力是A769662的5-10倍。 |
| 英文描述 |
Information ex229 (compound 991) EX229 (compound 991) is a potent AMPK activator that is 5-10-fold more potent than A769662 in activating AMPK. Targets AMPK In vitro EX229 activates AMPK in incubated rat epitrochlearis skeletal muscle and incubation of rat skeletal muscle with ex229 increases glucose uptake. The stimulation of skeletal muscle glucose uptake by ex229 is PI3K/PKB-independent, while AMPK-dependent. ex229 increases fatty acid oxidation and glucose uptake in L6 myotubes. |