EGF Receptor Substrate 2 (Phospho-Tyr5)
规格
| Cas Number | 149261-42-7 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 50 mg/mL (37.64 mM; Need ultrasonic) |
| 过滤标签 | EGFR,JAK/STAT Signaling,Protein Tyrosine Kinase/RTK |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 表皮生长因子受体底物 2（Phospho-Tyr5）是从表皮生长因子受体（EGFR）的自身磷酸化位点（Tyr 992）提取的具有生物活性的多肽。 |
| 英文描述 |
EGF Receptor Substrate 2 (Phospho-Tyr5) is a biologically active peptide derived from an autophosphorylation site (Tyr 992 ) of epidermal growth factor receptor (EGFR). In Vitro DADEpYLIPQQG is a generalized PTPase substrate. Both CAV GST-VP2 and TLMV GST-ORF2 are shown to have PTPase activity using both ENDpYINASL and DADEpYLIPQQG. Steady state activities for the reaction of 5 μg of CAV GST-VP2 with ENDpYINASL and DADEpYLIPQQG are 100 and 208%, respectively, of those seen for 2 units of TC-PTP. In the context of DADEpYLIPQQG, the minimal sizes recognized by PTPα are either ADEpYLI or DADEpY-NH2. The k cat /K m value for the parent peptide DADEpYLIPQQG (EGFR 988-998 ) is 1090-fold higher than Tyr(P). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |