FAPI-46
规格
| Cas Number | 2374782-04-2 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 100 mg/mL (112.87 mM; Need ultrasonic) DMSO : 100 mg/mL (112.87 mM; Need ultrasonic) |
| 过滤标签 | FAP,Immunology/Inflammation |
| 储存温度 | 2-8°C储存,干燥 |
| 运输条件 | 冰袋运输 |
| 生化和生理学机理 | FAPI-46 是一种基于喹啉的成纤维细胞活化蛋白（FAP）靶向放射性示踪剂。FAPI-46 具有较高的肿瘤摄取率和较长的肿瘤蓄积时间。FAPI-46 可用于多种不同癌症的肿瘤成像。 |
| 英文描述 |
FAPI-46 is a quinoline-based fibroblast activation protein (FAP) -targeted radiotracer. FAPI-46 has higher tumor uptake and prolonged tumor accumulation. FAPI-46 can be used for tumor imaging of a multitude of different cancers In Vitro FAPI-46 (1-24 h) robustly binds to human FAP in human FAP-expressing HT-1080 cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo FAPI-46 (i.v.) shows improved ratios of tumor to liver, kidney, and brain uptake, resulting in an enhanced image contrast for PET imaging . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:fibroblast activation protein (FAP) |