Fmoc-Ala-Glu-Asn-Lys-NH2
规格
| Cas Number | 220701-06-4 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 10mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 100 mg/mL (146.68 mM; ultrasonic and warming and heat to 80°C) |
| 过滤标签 | Amyloid-β,神经元信号传导 |
| 储存温度 | 避光,充氩,干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | Fmoc-Ala-Glu-Asn-Lys-NH2是一种选择性天冬酰胺内肽酶（AEP）抑制肽，能抑制淀粉样前体蛋白（APP）的裂解。AEP是一种受pH值控制的半胱氨酸蛋白酶，在衰老过程中被激活并介导APP的蛋白水解过程 |
| 英文描述 |
Fmoc-Ala-Glu-Asn-Lys-NH2 is a selective asparagine endopeptidase (AEP) inhibitor peptide and suppresses amyloid precursor protein (APP) cleavage. AEP, a pH-controlled cysteine proteinase, is activated during ageing and mediates APP proteolytic processing. In Vitro Fmoc-Ala-Glu-Asn-Lys-NH2 antagonizes APP processing by AEP, whereas other small molecular inhibitors and inactive peptide AEQK were without effect. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |