G6PDi-1
规格
| Cas Number | 2457232-14-1 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 100mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | Solubility (25°C) In vitro DMSO: 57 mg/mL (200.46 mM); Water: Insoluble; Ethanol: Insoluble; |
| 简短描述 | 脱氢酶抑制剂 |
| 英文简短描述 | Dehydrogenase Inhibitors |
| 过滤标签 | PDI,Cell Cycle/DNA Damage,Metabolic Enzyme/Protease |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | G6PDi-1 是一种有效的葡萄糖-6-磷酸脱氢酶（G6PD）抑制剂。G6PDi-1 可消耗 NADPH 并减少炎性细胞因子的产生。 |
| 英文描述 |
Information G6PDi-1 G6PDi-1 is an effective inhibitor of glucose-6-phosphate dehydrogenase (G6PD) . G6PDi-1 depletes NADPH and decreases inflammatory cytokine production. Targets G6PD ; NADPH In vitro G6PDi-1 effectively inhibits G6PD. Across a range of cultured cells, G6PDi-1 depletes NADPH most strongly in lymphocytes. In T cells but not macrophages, G6PDi-1 markedly decreases inflammatory cytokine production. In neutrophils, it suppresses respiratory burst. Cell Research(from reference) Cell lines：HepG2 cells, HCT116 cells, T cells Concentrations：25 μM, 50 μM, 75 μM, 100 μM Incubation Time：2 h, 4 h, 6 h |