GW438014A
规格
| Cas Number | 469861-49-2 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 250 mg/mL (571.42 mM; Need ultrasonic) |
| 过滤标签 | Neuropeptide Y Receptor,GPCR/G Protein,神经元信号传导 |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | GW438014A 是一种强效的选择性 NPY-Y5 受体拮抗剂。GW438014A 可抑制肥胖啮齿动物的食物摄入量并减少体重增加。 |
| 英文描述 |
GW438014A is a potent and selective NPY-Y5 receptor antagonist. GW438014A inhibits food intake and reduces body weight gain in obese rodents. In Vivo GW438014A (10 mg/kg; i.p.; daily, for 7 d) inhibits spontaneous as well as overnight fasting-induced and NPY-induced feeding in rats and in food-deprived genetically obese ob/ob mice . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: obese ob/ob mice Dosage: 10 mg/kg Administration: intraperitoneal injection; daily, for 7 d Result: Decreased the rate of weight gain in both lean and obese rats. Form:Solid |