Imiquimod hydrochloride
规格
| Cas Number | 99011-78-6(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | Toll-like Receptor (TLR),HSV,SARS-CoV冠状病毒,Immunology/Inflammation,Anti-infection,Compound libraries |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 盐酸咪喹莫特（R 837 盐酸盐）是一种免疫反应调节剂，是一种选择性类毒素受体 7（TLR7）激动剂。盐酸咪喹莫特在体内具有抗病毒和抗肿瘤作用。盐酸咪喹莫特可用于研究 |
| 英文描述 |
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19. In Vivo In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete\ncytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |