ICA-105574
规格
| Cas Number | 316146-57-3 |
| 规格或纯度 | Moligand™, ≥98% |
| 级别 | Moligand™ |
| 纯度 | ≥98% |
| 包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| Action Type | 激活剂,门控抑制剂 |
| Mechanism Of Action | K v10.1的门控抑制剂；K v11.1的激活剂 |
| 过滤标签 | Kv10.1 Gating inhibitor,Kv11.1 Activator |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | ICA-105574（ICA，3-硝基-N-[4-苯氧基苯基]-苯甲酰胺）是一种 hERG 激活剂，能与通道结合以消除失活，从而增加峰值电流幅度并缩短动作电位。ICA-105574 还能调节通道的激活动力学。 |
| 英文描述 |
Information ICA-105574 (ICA, 3-nitro-N-[4-phenoxyphenyl]-benzamide) is an activator of hERG that binds to the channel to remove inactivation, thus increasing peak current amplitude and shortening the action potential. ICA-105574 also modulates activation kinetics of the channel. |