Imiquimod hydrochloride
规格
Cas Number | 99011-78-6 |
规格或纯度 | ≥99% |
纯度 | ≥99% |
包装 | 100mg 或 200mg 或 500mg |
产品信息
品牌 | 阿拉丁 |
溶解性 | Methanol : 24 mg/mL (86.72 mM; Need ultrasonic) DMSO : 8 mg/mL (28.91 mM; ultrasonic and warming and heat to 50°C) H2O : 4.8 mg/mL (17.34 mM; Need ultrasonic) Ethanol : 3.85 mg/mL (13.91 mM; Need ultrasonic) |
过滤标签 | Toll-like Receptor (TLR),HSV,SARS-CoV冠状病毒,Immunology/Inflammation,Anti-infection |
储存温度 | 2-8°C储存,干燥 |
运输条件 | 冰袋运输 |
生化和生理学机理 | 盐酸咪喹莫特(R 837 盐酸盐)是一种免疫反应调节剂,是一种选择性类毒素受体 7(TLR7)激动剂。盐酸咪喹莫特在体内具有抗病毒和抗肿瘤作用。盐酸咪喹莫特可用于研究 |
英文描述 |
Imiquimod hydrochloride (R 837 hydrochloride), an immune response modifier, is a selective toll like receptor 7 (TLR7) agonist. Imiquimod hydrochloride exhibits antiviral and antitumor effects in vivo. Imiquimod hydrochloride can be used for the research of external genital, perianal warts, cancer and COVID-19. In Vivo In animal models, Imiquimod hydrochloride stimulates the innate immune response by increasing NK cell activity, activating macrophages to secrete\ncytokines and nitric oxide, and inducing proliferation and differentiation of B lymphocytes. Imiquimod hydrochloride stimulates the innate immune response through induction, synthesis, and release of cytokines, including interferon-a (IFN-α), interleukin (IL)-6, and tumour necrosis factor (TNF)-α . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |