INCB059872 dihydrochloride

https://www.xunlan.net/web/image/product.template/204561/image_1920?unique=dff1a7d

¥ 15,000.90 15000.9 CNY ¥ 15,000.90

¥ 3,500.90

Not Available For Sale

规格或纯度 ≥98%
货号(SKU) I659229
品牌 阿拉丁
  • 包装

此组合不存在。

条款和条件
30天退款保证
运输:2-3 个工作日

规格


Cas Number I659229
规格或纯度 ≥98%
纯度 ≥98%
包装 10mg1mg5mg

产品信息


品牌 阿拉丁
溶解性 DMSO : 3.57 mg/mL (7.77 mM; ultrasonic and warming and heat to 60°C)
过滤标签 表观遗传学,Histone Demethylase
储存温度 2-8°C储存,干燥
运输条件 冰袋运输
英文描述

INCB059872 dihydrochloride is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 ( LSD1 ) inhibitor. INCB059872 dihydrochloride can be used for the research of myeloid leukemia.

Appearance:Solid

IC50& Target:KDM1/LSD1

In Vitro:INCB059872 (25 nM; 48 hours; 293T cells) dihydrochloride increases enhancer activity and gene expression. INCB059872 (25 nM; 24 hours; THP-1 cells) dihydrochloride makes THP-1 show a growth defect within one cell doubling time or approximately 3 days

In Vivo:INCB059872 (10mg/kg; p.o.; 0, 4, or 6 days; C57BL/6J mice) dihydrochloride makes single-cell RNA-seq revealing changes in bone marrow progenitor populations. MCE has not independently confirmed the accuracy of these methods. They are for reference o

Biological Activity:INCB059872 dihydrochloride is a potent, orally active, selective and irreversible Lysine-Specific Demethylase 1 ( LSD1 ) inhibitor. INCB059872 dihydrochloride can be used for the research of myeloid leukemia.

技术规格说明书


质检证书(CoA,COO,BSE/TSE)