Isoviolanthin
规格
| Cas Number | 40788-84-9 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 250 mg/mL (432.14 mM; Need ultrasonic) |
| 英文简短描述 | Flavonoids Flavones Phenols Polyphenols |
| 过滤标签 | TGF-beta/Smad,Stem Cell/Wnt,Flavonoids Flavones Phenols Polyphenols |
| 储存温度 | 避光,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 异黄酮黄酮苷是一种黄酮苷，它能通过TGF-β/Smad和PI3K/Akt/mTOR途径，使上皮-间质转化（EMT）失活，从而显著抑制TGF-β1介导的HCC细胞的迁移和侵袭。异紫罗兰黄素没有细胞毒性作用。 |
| 英文描述 |
Isoviolanthin, a flavonoid glycoside, could markedly inhibit TGF-β1-mediated migration and invasion by deactivating epithelial-mesenchymal transition (EMT) via the TGF-β/Smad and PI3K/Akt/mTOR pathways in HCC cells. Isoviolanthin exhibits no cytotoxic effects on normal liver LO2 cells. Form:Solid |