LCKLSL hydrochloride
规格
| Cas Number | L658992 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 25 mg/mL (35.10 mM; Need ultrasonic) H2O : 10 mg/mL (14.04 mM; Need ultrasonic) |
| 过滤标签 | Others |
| 储存温度 | 避光,干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 英文描述 |
LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2 . LCKLSL hydrochloride also inhibits the generation of plasm Appearance:Solid IC50& Target:Annexin A2 (AnxA2) In Vitro:In human retinal microvascular endothelial cells (RMVECs), treatment with LCKLSL (0-2 mg) inhibits the generation of plasmin and suppresses the VEGF-induced activity of tPA under hypoxic conditions. MCE has not independently confirmed the accuracy of In Vivo:Application of LCKLSL in two in vivo models (in chicken chorioallantoic membrane and murine Matrigel plug assays) of angiogenesis demonstrates suppression of the angiogenic responses. Treatment with the LCKLSL peptide significantly decreases the vascular Biological Activity:LCKLSL hydrochloride is a N-terminal hexapeptide and a competitive annexin A2 (AnxA2) inhibitor. LCKLSL hydrochloride potently inhibits the binding of tissue plasminogen activator (tPA) to AnxA2 . LCKLSL hydrochloride also inhibits the generation of plasm |