m-PEG11-acid
规格
| Cas Number | 2280998-74-3 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 100mg 或 50mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 100 mg/mL (183.61 mM; Need ultrasonic) |
| 过滤标签 | PROTAC连接器,ADC Linker,Antibody-drug Conjugate/ADC Related,PROTAC |
| 储存温度 | 避光,-20°C储存,充氩 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | m-PEG11-acid 是一种不可分解的 11 单元 PEG ADC 连接剂，可用于合成抗体药物共轭物 (ADC)。 |
| 英文描述 |
m-PEG11-acid is a non-cleavable 11 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs) m-PEG11-acid is also a PEG-based PROTAC linker that can be used in the synthesis of PROTACs . In Vitro ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker. PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Liquid IC50& Target:PEGs|Non-cleavable |