MYF-01-37
规格
| Cas Number | 2416417-65-5 |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 溶解性 | Solubility (25°C) In vitro DMSO: 60 mg/mL (201.13 mM); Ethanol: 60 mg/mL (201.13 mM); Water: Insoluble; |
| 简短描述 | TEAD 抑制剂 |
| 英文简短描述 | TEAD Inhibitors |
| 过滤标签 | Compound libraries |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | MYF-01-37 是一种新型的 TEAD 共价抑制剂，与 TEAD2 蛋白孵育时靶向 Cys380。 |
| 描述 |
MYF-01-37 是一种与TEAD2蛋白一起孵育的靶向Cys380的新型 TEAD 的共价抑制剂。 |
| 英文描述 |
Information MYF-01-37 MYF-01-37 is a novel covalent inhibitor of TEAD targeting Cys380 when incubated with the TEAD2 protein. Targets TEAD In vitro MYF-01-37 is developed as a covalent binder to TEAD, targeting Cys380 when incubated with the TEAD2 protein (C359 in TEAD1). Pretreating cells with MYF-01-37 leads to loss of direct TEAD pull-down by biotin-MYF-01-037 from whole-cell lysate, confirming MYF-01-037 binding to TEAD in cells. Cell Research(from reference) Cell lines：PC9 cells Concentrations：10 μM, 1 μM Incubation Time：6 h |