MK-0941
规格
| Cas Number | 1137916-97-2(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | Glucokinase,Metabolic Enzyme/Protease,Compound libraries |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | MK-0941 是一种强效、具有口服活性的异源葡萄糖激酶激活剂，在 2.5 mM 和 10 mM 葡萄糖存在下，其对重组人葡萄糖激酶的 EC 50 s 分别为 240 和 65 nM。MK-0941 具有治疗 2 型糖尿病的潜力 |
| 英文描述 |
MK-0941 is a potent, orally active and allosteric glucokinase activator, with EC 50 s of 240 and 65 nM for recombinant human glucokinase in the presence of 2.5 and 10 mM glucose, respectively. MK-0941 has potential in the treatment of type 2 diabetes IC50& Target:EC50: 240 nM (Recombinant human glucokinase, 2.5 mM glucose), 65 nM (Recombinant human glucokinase, 10 mM glucose) |