Nebracetam hydrochloride
规格
| Cas Number | 1177279-49-0(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | mAChR,GPCR/G Protein,神经元信号传导,Compound libraries |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 盐酸奈布拉西坦是一种促智 M 1 -muscarinic 激动剂，可引起细胞内 Ca 2+ 浓度升高。盐酸奈布拉西坦提高[Ca 2+ ] i 的 EC 50 为 1.59 毫摩尔。 |
| 英文描述 |
Nebracetam hydrochloride, a nootropic M 1 -muscarinic agonist, induces a rise of intracellular Ca 2+ concentration. Nebracetam hydrochloride exhibits an EC 50 of 1.59 mM for elevating [Ca 2+ ] i. In Vivo Nebracetam (10 mg/kg, p.o.) involves not only cholinergic mechanisms but also involves lymbic and hippocampal noradrenergic mechanisms. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Animal Model: Male Wistar rats weighing 200-250 g. Dosage: 10, 20 mg/kg. Administration: P.O. (single dose). Result: Able to correct this scopolamine-induced disruption of spatial cognition. |