NFAT Inhibitor-2
规格
| Cas Number | 422546-87-0 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 100mg 或 50mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 125 mg/mL (279.97 mM; Need ultrasonic) |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | NFAT Inhibitor-2 是一种强效的钙调素系 NFAT 信号抑制剂。钙调磷酸酶是一种丝氨酸/苏氨酸蛋白磷酸酶，受 Ca2+ 和钙调素调节。NFAT Inhibitor-2 具有研究炎症性疾病（一种自身免疫性疾病）的潜力。 |
| 英文描述 |
NFAT Inhibitor-2 is a potent inhibitor of calcineurin NFAT signalling. Calcineurin is a serine/threonine protein phosphatase regulated by Ca2+ and calmodulin. NFAT Inhibitor-2 has the potential for the research of inflammatory disease, an autoimmune disorder, a cardiovascular disease , a neurodegenerative disease, a disease occurring with uncontrolled cell proliferation and/or differentiation, an angiogenesis-related disease, an allergy, anaphylaxis and alopecia (extracted from patent WO2016207212A1, compound 17). Form:Solid |