Oxyntomodulin
规格
| Cas Number | 62340-29-8 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 100 mg/mL (22.61 mM; Need ultrasonic) |
| 过滤标签 | GCGR,GPCR/G Protein |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | Oxyntomodulin 是一种 37 个氨基酸的肽类激素，是一种 Glukagon-like peptide 1（GLP-1）受体激动剂。 |
| 英文描述 |
Oxyntomodulin, a 37-amino acid peptide hormone, is a Glukagon-like peptide 1 (GLP-1) receptor agonist. In Vitro Oxyntomodulin is a peptide hormone released from the gut in post-prandial state that activates both the Glukagon-like peptide-1 receptor (GLP1R) and the Glukagon receptor (GCGR) resulting in superior body weight lowering to selective GLP1R agonists. Oxyntomodulin is mainly produced in gut endocrine L-cells by processing of the preproGlukagon precursor by prohormone convertase 1/3. Oxyntomodulin is a full agonist in cell lines over expressing the human GLP1R and GCGR-mediated cAMP accumulation although with reduced affinity compared to GLP-1 and Glukagon. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |