二硫化吡啶甲基丙烯酸乙酯

吡啶基二硫化甲基丙烯酸乙酯是一种基于甲基丙烯酸酯的单体，用于合成聚（吡啶基二硫化甲基丙烯酸乙酯）[p（PDSMA）]和其他共聚物。p（PDSMA）包含一个受保护的侧基硫醇，可用于通过硫醇-二硫键交换反应进行聚合后官能化。另外，反应进程通常可以通过吸收光谱法进行监测，因为释放的 2-吡啶硫酮的光谱特征（λ max= 375 nm）与聚合物中的吡啶基二硫化官能度（λ max= 280 nm）明显不同。由于它们的多功能性，这些材料已用于多种生物医学应用中，例如聚合物-生物分子缀合物的合成和

应用

Pyridyl disulfide ethyl methacrylate is a methacylate-based monomer used in the synthesis of poly(pyridyl disulfide ethyl methacrylate) [p(PDSMA)] and other copolymers. p(PDSMA) contains a pendant, protected thiol that can be used for post-polymerization functionalization via thiol-disulfide exchange reactions. Additionally, reaction progress can be typically monitored by absorption spectroscopy as the spectroscopic signature of the released 2-pyridinethione (λ max = 375 nm) is distinctly different from the pyridyl disulfide functionality (λ max = 280 nm) in the polymer. Due to their versatility, these materials have been used in a wide variety of biomedical applications such as the synthesis of polymer-biomolecule conjugates and drug delivery applications.}