p63 Mouse mAb

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规格或纯度 无载体, ExactAb™, 已验证, 高性能, 见COA
货号(SKU) Ab119899
品牌 阿拉丁
  • 包装

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条款和条件
30天退款保证
运输:2-3 个工作日

规格

Cas Number
规格或纯度 无载体, ExactAb™, 已验证, 高性能, 见COA
级别 无载体,ExactAb™,已验证,高性能
包装 1ml50μl100μl20μl10μl

产品信息

别名 AIS antibody; Amplified in squamous cell carcinoma antibody; B(p51A) antibody; B(p51B) antibody; Chronic ulcerative stomatitis protein antibody; CUSP antibody; DN p63 alpha 1 antibody; DNp63 antibody; EEC3 antibody; id:ibd3516 antibody; Keratinocyte transcription factor antibody; Keratinocyte transcription factorKET antibody; KET antibody; LMS antibody; MGC115972 antibody; MGC192897antibody; NBP antibody; OFC8 antibody; OTTHUMP00000209732 antibody; OTTHUMP00000209733antibody; OTTHUMP00000209734antibody; OTTHUMP00000209735 antibody; OTTHUMP00000209737 antibody; OTTHUMP00000209738 antibody; OTTHUMP00000209739 antibody; OTTHUMP00000209740 antibody; OTTHUMP00000209741 antibody; OTTHUMP00000209742 antibody; OTTHUMP00000209743 antibody; OTTHUMP00000209744 antibody; p40 antibody; p51 antibody; P51/P63 antibody; p53-related protein p63 antibody; p53CP antibody; p63 antibody; P63_HUMAN antibody; p73H antibody; p73L antibody; RHS antibody; SHFM4 antibody; TAp63alpha antibody; TP53CP antibody; TP53L antibody; TP63 antibody; TP73L antibody; Transformation related protein 63antibody; Transformation-related protein 63 antibody; Trp53rp1 antibody; Trp63 antibody; Tumor protein 63 antibody; Tumor protein p53-competing protein antibody; Tumor protein p53-like antibody; Tumor protein p63 antibody; Tumor protein p63 deltaN isoform delta antibody; Tumor protein p73 antibody; Tumor protein p73-like antibody; 肿廇蛋白P63(TP63)单克隆抗体
品牌 阿拉丁
浓度 见COA
简短描述 mAb (D2); Mouse anti Human p63 Antibody; WB; Unconjugated
英文简短描述 mAb (D2); Mouse anti Human p63 Antibody; WB; Unconjugated
稳定性和储存 4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
阳性对照 WB: A431 cell lysate.
组织特异性 Widely expressed, notably in heart, kidney, placenta, prostate, skeletal muscle, testis and thymus, although the precise isoform varies according to tissue type. Progenitor cell layers of skin, breast, eye and prostate express high levels of DeltaN-type isoforms. Isoform 10 is predominantly expressed in skin squamous cell carcinomas, but not in normal skin tissues.
轻链类型 kappa
防腐剂(Preservatives) 0.02% Sodium azide
过滤标签 Gene ID:8626,Accession#:Q9H3D4,p63,TP63
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
Clonality 单克隆抗体
克隆号 D2
形式 Whole IgG
Accession ID Q9H3D4
物理形态 液体
特异性 Tumor protein 63
Species reactivity(Reacts with) 人(Human),猪(Pig)
免疫原 Recombinant TP63 expressed in E.coli (AA 540~680)
Conjugate Unconjugated
纯化方法 Protein A + Protein G affinity purified
储存缓冲液 10mM PBS, 50% Glycerol, 0.02% Sodium azide, pH7.4
亚型 Mouse IgG2b
Immunogen species 人(Human)
Host species 小鼠(Mouse)
靶标动物 Human
Source 杂交瘤细胞培养上清
英文描述

Mouse anti Human p63 Antibody, Monoclonal (D2), could be used for WB and so on.
Application:
WB: 0.01-2 µg/mL
Protein Function
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge.

SDS-PAGE 150 kDa