PGS-IN-1
规格
| Cas Number | 102271-49-8 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg 或 20mg |
产品信息
| 品牌 | 阿拉丁 |
| 过滤标签 | Lipoxygenase,PGE synthase,Metabolic Enzyme/Protease,Immunology/Inflammation |
| 储存温度 | -20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | PGS-IN-1 是一种强效的前列腺素合成酶（PGS）抑制剂，IC50 为 0.28 μM；还能抑制 5-脂氧合酶，IC50 为 1.05 μM。 |
| 英文描述 |
PGS-IN-1 is a potent inhibitor of prostaglandin synthetase (PGS) with an IC 50 of 0.28 μM; also inhibits 5-lipoxygenase with an IC 50 of 1.05 μM. In Vitro The synthesized α-benzulidene-γ-butyrolactones are pure isomers (either cis or trans ). PGS-IN-1 is the trans isomer. PGS-IN-1 exhibits potent antiinflammatrory and PGS inhibitory activity (IC 50 =0.28 μM). PGS-IN-1 also shows potent inhibitory activity against 5-lipoxygenase (IC 50 =1.05 μM). MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:5-Lipoxygenase 1.05 μM (IC 50 ) |