Ropidoxuridine
规格
| Cas Number | 93265-81-7(DMSO) |
| 规格或纯度 | 10mM in DMSO |
| 包装 | 1ml |
产品信息
| 品牌 | 阿拉丁 |
| 浓度 | 10mM in DMSO |
| 过滤标签 | Compound libraries |
| 储存温度 | -80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 罗匹多尿苷（IPdR）是一种新型口服卤代胸苷类似物，是一种可用于人类肿瘤的潜在放射增敏剂。 |
| 英文描述 |
Ropidoxuridine (IPdR) is a novel orally available, halogenated thymidine analog and is a potential radiosensitizer for use in human tumors. In Vitro Ropidoxuridine is an orally bioavailable pro-drug of IUdR (5-iodo-2'-deoxyuridine). Ropidoxuridine demonstrates strong synergy effects with Alisertib at clinically relevant concentrations. MCE has not independently confirmed the accuracy of these methods. They are for reference only. In Vivo In an orthotopic tumor model, Ropidoxuridine (750 mg/kg/day) and Alisertib (30 mg/kg/day) demonstrate strong synergy effects . MCE has not independently confirmed the accuracy of these methods. They are for reference only. |