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别名
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BAF; BAF_HUMAN; BANF 1; BANF1; Barrier to autointegration factor 1; Barrier to autointegration factor; Barrier-to-autointegration factor; BCRG 1; BCRG1; BCRP 1; BCRP1; Breakpoint cluster region protein 1; D14S1460; MGC111161; BAF antibody; BAF_HUMAN antibody; BANF 1 antibody; BANF1 antibody; Barrier to autointegration factor 1 antibody; Barrier to autointegration factor antibody; Barrier-to-autointegration factor antibody; BCRG 1 antibody; BCRG1 antibody; BCRP 1 antibody; BCRP1 antibody; Breakpoint cluster region protein 1 antibody; D14S1460 antibody; MGC111161 antibody; NGPS antibody; 障碍自整合蛋白BAF抗体
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品牌
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阿拉丁
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浓度
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0.825 mg/mL
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简短描述
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Recombinant; Rabbit anti Human BANF1/BAF Antibody; WB; Unconjugated
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英文简短描述
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Recombinant; Rabbit anti Human BANF1/BAF Antibody; WB; Unconjugated
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稳定性和储存
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4°C 短期储存（1-2 周）。-20°C下长期保存（24个月）。收货后建议分装。避免冷冻/解冻循环。
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阳性对照
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WB: HeLa, MCF7, Hep G2, HEK293, Jurkat and NIH/3T3 cell lysates.
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组织特异性
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Widely expressed. Expressed in colon, brain, heart, kidney, liver, lung, ovary, pancreas, placenta, prostate, skeletal muscle, small intestine, spleen and testis. Not detected in thymus and peripheral blood leukocytes.
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结构域
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Has a helix-hairpin-helix (HhH) structural motif conserved among proteins that bind non-specifically to DNA.
LEM domain proteins bind centrally on the BAF dimer, whereas DNA binds to the left and right sides.
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轻链类型
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kappa
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防腐剂（Preservatives）
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0.02% Sodium azide
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过滤标签
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Gene ID:8815,Accession#:O75531,BANF1,BAF
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储存温度
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-20°C储存,避免反复冻融
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运输条件
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超低温冰袋运输
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Clonality
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重组抗体
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形式
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Whole IgG
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Accession ID
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O75531
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物理形态
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液体
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特异性
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BANF1
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Species reactivity（Reacts with)
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人(Human),小鼠(Mouse),大鼠(Rat)
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免疫原
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A synthetic peptide derived from human BANF1 (AA 1-45)
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Conjugate
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Unconjugated
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纯化方法
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Protein A purified
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储存缓冲液
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10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH 7.4
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亚型
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Rabbit IgG
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Immunogen species
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人(Human)
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Host species
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兔(Rabbit)
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靶标动物
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Human
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Source
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293细胞培养上清
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英文描述
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Rabbit anti Human BANF1/BAF Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD.
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SDS-PAGE
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150 kDa
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