Recombinant Human Sonic Hedgehog/Shh (C24II) Protein

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规格或纯度 Carrier Free, ≥95%(SDS-PAGE)
货号(SKU) rp188214
品牌 阿拉丁
  • 包装

此组合不存在。

条款和条件
30天退款保证
运输:2-3 个工作日

规格


Cas Number
规格或纯度 Carrier Free, ≥95%(SDS-PAGE)
级别 无载体
纯度 ≥95%(SDS-PAGE)
包装 1mg100μg10μg50μg

产品信息


品牌 阿拉丁
Animal free No
Carrier free Yes
预测分子量 19.7 kDa
氨基酸 24-197 (C24II) aa
Protein length 蛋白片段
表达系统 大肠杆菌
生物活性 Testing in progress
蛋白标签 No tag
序列 IIGPGRGFGKRRHPKKLTPLAYKQFIPNVAEKTLGASGRYEGKISRNSERFKELTPNYNPDIIFKDEENTGADRLMTQRCKDKLNALAISVMNQWPGVKLRVTEGWDEDGHHSEESLHYEGRAVDITTSDRDRSKYGMLARLAVEAGFDWVYYESKAHIHCSVKAENSVAAKSGG
复溶(Reconstitution) We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
简短描述 Carrier Free, ≥95% (SDS-PAGE), E. coli, No tag, 24-197 aa
英文简短描述 Carrier Free, ≥95% (SDS-PAGE), E. coli, No tag, 24-197 aa
稳定性和储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
过滤标签 Gene ID:6469,Accession#:Q15465,Sonic Hedgehog,SHH
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
Accession ID Q15465
物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, 100 mM NaCl, pH 7.4
内毒素浓度 <1.0 EU/μg
Source 重组表达
英文描述

Protein Function:
Binds to the patched (PTC) receptor, which functions in association with smoothened (SMO), to activate the transcription of target genes. In the absence of SHH, PTC represses the constitutive signaling activity of SMO. Also regulates another target, the gli oncogene. Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction.

SDS-PAGE 19.3 kDa, under reducing conditions; 19.3 kDa, under non-reducing conditions

技术规格说明书


质检证书(CoA,COO,BSE/TSE)