Recombinant LysRS Antibody
规格
Cas Number | |
规格或纯度 | 重组, ExactAb™, 已验证, 见COA |
级别 | 重组,ExactAb™,已验证 |
包装 | 1ml 或 50μl 或 100μl 或 10μl |
产品信息
别名 | CMTRIB antibody; DFNB89 antibody; EC 6.1.1.6 antibody; KARS 1 antibody; KARS 2 antibody; KARS antibody; KARS1 antibody; KARS2 antibody; KIAA0070 antibody; KRS antibody; Lysine tRNA ligase antibody; Lysine--tRNA ligase antibody; LysRS antibody; Lysyl tRNA synthetase antibody; Lysyl-tRNA synthetase antibody; SYK_HUMAN antibody |
品牌 | 阿拉丁 |
浓度 | 见COA |
简短描述 | LysRS 兔多克隆 |
英文简短描述 | Recombinant; Rabbit anti Human LysRS Antibody; WB; Unconjugated |
稳定性和储存 | 4°C 下运输。在 +4°C 下短期储存(1-2 周)。收货后建议分装。长期储存于 -20°C。 |
阳性对照 | WB: Jurkat, HeLa, Hep G2 and HEK293 cell lysates. |
结构域 | The N-terminal domain (1-65) of the cytoplasmic isoform is a functional tRNA-binding domain (By similarity), is required for nuclear localization, is involved in the interaction with DARS, but has a repulsive role in the binding to EEF1A1. A central domain (208-259) is involved in homodimerization and is required for interaction with HIV-1 GAG and incorporation into virions. The C-terminal domain (452-597) is not required for interaction with AIMP2. |
轻链类型 | kappa |
防腐剂(Preservatives) | 0.02% Sodium azide |
过滤标签 | Gene ID:3735,Accession#:Q15046,LysRS,KARS1,CMTRIB |
储存温度 | -20°C储存,避免反复冻融 |
运输条件 | 超低温冰袋运输 |
Clonality | 重组抗体 |
形式 | Whole IgG |
Accession ID | Q15046 |
物理形态 | 液体 |
特异性 | KARS1 |
Species reactivity(Reacts with) | 人(Human),小鼠(Mouse),大鼠(Rat) |
免疫原 | A synthetic peptide derived from human Lysine tRNA ligase (AA 550-597) |
Conjugate | Unconjugated |
纯化方法 | Protein A purified |
储存缓冲液 | 10mM PBS, 150mM NaCl, 50% Glycerol, 0.05% BSA, 0.02% Sodium azide, pH7.4 |
亚型 | Rabbit IgG |
Immunogen species | 人(Human) |
Host species | 兔(Rabbit) |
靶标动物 | Human,Mouse,Rat |
Source | 293细胞培养上清 |
生化和生理学机理 | Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. When secreted, acts as a signaling molecule that induces immune response through the activation of monocyte/macrophages. Catalyzes the synthesis of diadenosine oligophosphate (Ap4A), a signaling molecule involved in the activation of MITF transcriptional activity. Interacts with HIV-1 virus GAG protein, facilitating the selective packaging of tRNA(3)(Lys), the primer for reverse transcription initiation. |
英文描述 |
Rabbit anti Human LysRS Antibody, Recombinant, could be used for WB and so on. |
SDS-PAGE | 150 kDa |