Recombinant PHD1/prolyl hydroxylase Antibody

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规格或纯度 ExactAb™, Validated, 重组, 0.5 mg/mL
货号(SKU) Ab121561
品牌 阿拉丁
  • 包装

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条款和条件
30天退款保证
运输:2-3 个工作日

规格

Cas Number
规格或纯度 ExactAb™, Validated, 重组, 0.5 mg/mL
级别 重组,ExactAb™,已验证
包装 1ml50μl100μl10μl

产品信息

别名 DKFZp434E026 antibody; EGL nine (C.elegans) homolog 2 antibody; Egl nine homolog 2 (C. elegans) antibody; Egl nine homolog 2 antibody; EGLN 2 antibody; EGLN2 antibody; EGLN2_HUMAN antibody; EIT 6 antibody; EIT6 antibody; Estrogen-induced tag 6 antibody; HIF P4H 1 antibody; HIF PH1 antibody; HIF prolyl hydroxylase 1 antibody; HIF-PH1 antibody; HIF-prolyl hydroxylase 1 antibody; HIFPH 1 antibody; HIFPH1 antibody; HPH 3 antibody; HPH-1 antibody; HPH-3 antibody; HPH3 antibody; Hypoxia inducible factor prolyl hydroxylase 1 antibody; Hypoxia-inducible factor prolyl hydroxylase 1 antibody; P4H1 antibody; PHD 1 antibody; PhD1 antibody; prolyl hydroxylase domain containing protein 1 antibody; Prolyl hydroxylase domain-containing protein 1 antibody
品牌 阿拉丁
浓度 0.5 mg/mL
简短描述 Recombinant; Rabbit anti Human PHD1/prolyl hydroxylase Antibody; WB; Unconjugated
英文简短描述 Recombinant; Rabbit anti Human PHD1/prolyl hydroxylase Antibody; WB; Unconjugated
稳定性和储存 4°C 短期储存(1-2 周)。-20°C下长期保存(24个月)。收货后建议分装。避免冷冻/解冻循环。
阳性对照 WB: HeLa, A549, U-2 OS, MCF7 and MDA-MB-231 cell lysates.
组织特异性 Expressed abundantly in all tissues with highest expression in testis. Expressed in hormone responsive tissues, including normal and cancerous mammary, ovarian and prostate epithelium.
防腐剂(Preservatives) 0.01% Sodium azide
过滤标签 prolyl hydroxylase,EGLN2,PHD1,Gene ID:112398,Accession#:Q96KS0
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
Clonality 重组抗体
形式 Whole IgG
Accession ID Q96KS0
物理形态 液体
特异性 EGLN2
Species reactivity(Reacts with) 人(Human),大鼠(Rat)
免疫原 A synthetic peptide derived from human PHD1/prolyl hydroxylase (AA 21-34)
Conjugate Unconjugated
纯化方法 Antigen affinity purified
储存缓冲液 50mM Tris-Glycine, 150mM NaCl, 40% Glycerol, 0.05% BSA, 0.01% Sodium azide, pH 7.4
亚型 Rabbit IgG
Immunogen species 人(Human)
Host species 兔(Rabbit)
靶标动物 Human
Source 细胞培养上清
英文描述

Rabbit anti Human PHD1/prolyl hydroxylase Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Catalyzes the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates HIF-1 alpha at 'Pro-402' and 'Pro-564', and HIF-2 alpha. Functions as a cellular oxygen sensor and, under normoxic conditions, targets HIF through the hydroxylation for proteasomal degradation via the von Hippel-Lindau ubiquitination complex. May play a role in cell growth regulation. Isoform p40 and isoform p43 exhibit the same level of activity.

SDS-PAGE 150 kDa

技术规格说明书


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