(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine
规格
| Cas Number | 2347517-69-3 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : ≥ 170 mg/mL (226.39 mM) |
| 过滤标签 | 羟基聚乙二醇,HIF/HIF Prolyl-Hydroxylase,PROTACs,TGF-beta/Smad,Stem Cell/Wnt,Metabolic Enzyme/Protease,PROTAC,PROTAC linker,DBCO PEG,Vinylsulfone |
| 储存温度 | 2-8°C储存,避光,干燥 |
| 运输条件 | 冰袋运输 |
| 生化和生理学机理 | (S,R,S)-AHPC-C2-酰胺-苯并呋喃甲基吡啶是一种双靶点 PROTAC，不仅能靶向泛素化和降解 Smad3，还能提高 HIF-α 蛋白水平。(S,R,S)-AHPC-C2-酰胺-苯并呋喃甲基吡啶具有多途径作用 |
| 英文描述 |
(S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine is a dual target PROTAC that can not only target to the ubiquitination and degradation of Smad3 but also improve the HIF-α protein level. (S,R,S)-AHPC-C2-amide-benzofuranylmethyl-pyridine has a multi-path anti-fibrosis function and a renal protection function for research of renal anemia. Form:Solid |