(S)-UFR2709 hydrochloride
规格
| Cas Number | 2934318-93-9 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 100 mg/mL (391.02 mM; Need ultrasonic) DMSO : 50 mg/mL (195.51 mM; Need ultrasonic) |
| 过滤标签 | nAChR,神经元信号传导,膜转运器/离子通道,Neuronal Signaling,Membrane Transporter/Ion Channel |
| 储存温度 | 2-8°C储存,充氩 |
| 运输条件 | 冰袋运输 |
| 描述 |
(S)-UFR2709 (hydrochloride) 是一种竞争性的 nAChR 拮抗剂，并显示出较强的亲和力，对 α4β2 nAChR 的亲和力比对 α7 nAChR 的高。(S)-UFR2709 (hydrochloride) 在偏好酒精的老鼠中减少焦虑，并且可以减少其酒精摄入和对酒精偏好。(S)-UFR2709 (hydrochloride) 是抗焦虑试剂，可用于研究尼古丁成瘾。
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| 英文描述 |
(S)-UFR2709 (hydrochloride) is a competitive nAChR antagonist and displays higher affinity for α4β2 nAChRs than for α7 nAChRs. (S)-UFR2709 (hydrochloride) decreases anxiety and reduces ethanol consumption and ethanol preference in alcohol-preferring rats. (S)-UFR2709 (hydrochloride) acts as an anxiolytic agent and can be used for the study of nicotine addiction.
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