(Sar1,Ile4,8)-Angiotensin II
规格
| Cas Number | 185461-45-4 |
| 规格或纯度 | ≥98% |
| 纯度 | ≥98% |
| 包装 | 10mg 或 1mg 或 5mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 100 mg/mL (108.92 mM; Need ultrasonic) |
| 过滤标签 | Angiotensin Receptor,GPCR/G Protein |
| 储存温度 | 避光,充氩,干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | (Sar1,Ile4,8)-血管紧张素 II 是一种功能选择性血管紧张素 II 1 型受体（AT1R）激动剂。(Sar1,Ile4,8)-血管紧张素 II 能增强胰岛素刺激的胰岛素受体（IR）信号传导和糖原合成。(Sar1,Ile4,8)-血管紧张素 II 有助于胰岛素刺激的胰岛素受体（IR）信号传导和糖原合成。 |
| 英文描述 |
(Sar1,Ile4,8)-Angiotensin II is a functionally selective angiotensin II type 1 receptor (AT1R) agonist. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated insulin receptor (IR) signaling and glycogen synthesis. (Sar1,Ile4,8)-Angiotensin II potentiates insulin-stimulated phosphorylation of Akt and GSK3α/β In Vitro (Sar1,Ile4,8)-Angiotensin II (30 μM; 30 min) increases the expression of insulin-stimulated phosphorylation of Akt and GSK3α/β in hepatocytes. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:Angiotensin II Type 1 |