SPOP-IN-6b dihydrochloride
规格
| Cas Number | S658950 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 50mg 或 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | DMSO : 41.67 mg/mL (72.66 mM; ultrasonic and warming and heat to 60°C) |
| 过滤标签 | Others |
| 储存温度 | 2-8°C储存,干燥 |
| 运输条件 | 冰袋运输 |
| 英文描述 |
SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM. Appearance:Solid In Vitro:SPOP-IN-6b dihydrochloride shows IC 50 s of 2-10.2 μM for A498, Caki-2, Ketr-3, 769-P, 0S-RC-2, and 786-0 cells. SPOP-IN-6b (0.1-3.0 μM; 10 hours) dihydrochloride can suppress SPOP activity, and then increase suppression cancer substrate protein PTEN In Vivo:SPOP-IN-6b (40-80mg/kg; intraperitoneal injection; daily; for 25 days; nude mice) dihydrochloride can slow down the growth of tumour by suppressing SPOP. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Biological Activity:SPOP-IN-6b dihydrochloride is a potent speckle-type POZ protein (SPOP) inhibitor with an IC 50 of 3.58 μM. |