Stafib-1
规格
Cas Number | 1688703-26-5 |
规格或纯度 | ≥95% |
纯度 | ≥95% |
包装 | 100mg 或 50mg 或 10mg 或 5mg 或 25mg |
产品信息
品牌 | 阿拉丁 |
溶解性 | DMSO : 100 mg/mL (166.00 mM; Need ultrasonic) |
过滤标签 | STAT,JAK/STAT Signaling,Stem Cell/Wnt |
储存温度 | -20°C储存 |
运输条件 | 超低温冰袋运输 |
生化和生理学机理 | Stafib-1 是 STAT5b SH2 结构域的首个选择性抑制剂,其 K i 为 44 nM,IC 50 为 154 nM。 |
英文描述 |
Stafib-1 is the first selective inhibitor of the STAT5b SH2 domain, with a K i of 44 nM and an IC 50 of 154 nM In Vitro Stafib-1 is the first small molecule which inhibits the STAT5b SH2 domain with more than 50-fold selectivity over STAT5a. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:STAT5b 154 nM (IC 50 ) |