Substance P(1-7) TFA
规格
| Cas Number | 2828433-22-1 |
| 规格或纯度 | ≥99% |
| 纯度 | ≥99% |
| 包装 | 10mg 或 5mg 或 25mg |
产品信息
| 品牌 | 阿拉丁 |
| 溶解性 | H2O : 50 mg/mL (49.31 mM; Need ultrasonic) |
| 过滤标签 | Neurokinin Receptor,GPCR/G Protein,神经元信号传导 |
| 储存温度 | 干燥,-80℃储存 |
| 运输条件 | 超低温冰袋运输 |
| 生化和生理学机理 | 物质 P(1-7) TFA 是神经肽物质 P (SP) 的一个片段。P(1-7) TFA 物质作用于脊髓束核时，会产生抑制和心动过缓的效果。 |
| 英文描述 |
Substance P(1-7) TFA is a fragment of the neuropeptide, substance P (SP). Substance P(1-7) TFA gives depressor and bradycardic effects when applied to the nucleus tractus solitarius. In Vivo Substance P(1-7) is found to act as a very potent antagonist against the SP-induced responses and is formed locally in the nigra after SP injection. It is proposed that Substance P(1-7) is an endogenous modulator of SP actions . Injection of low doses of Substance P(1-7) (1.0-4.0 pM simultaneously with SP or SP(5-11) (0.1 nM), reduce aversive behaviours induced by SP or SP(5- 11) significantly. These results indicate that SP(1-7) formed endogenously could modulate the actions of SP or SP(5-11) in the spinal cord. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid |